Summary: Krane et al. (2003)

The Indonesian prosimian, the slow loris Nycticebus coucang are known to inflict painful (occasionally fatal) bites that elicit anaphylaxis. The "venom" originates in the brachial organ. This organ is located in a naked area of skin on the inner arm surface. Krane et al. (2003) isolated a 18kDA protein (two 70-90 amino-acid chains with linking disulphide bonds) from the brachial organ. The N-termini of the protein chains were similar to an allergen from common house cats Felis catus, Fel d 1, suggesting the they exhibit inorganic cross- reactivity. This, together with the display of anaphylaxis and increased sensitivity to slow loris bites indicates that this slow loris protein is an allergen.